Advancing Genomics for Drug Development and Safety Evaluation
نویسندگان
چکیده
منابع مشابه
Advancing Drug Development for Respiratory Syncytial Virus
Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infections (LRTIs) in infants and children around the world, resulting in three million hospitalizations and several hundred thousand deaths annually, the vast majority of which occur in developing nations. Treatment options for RSV are limited, and efforts to produce a vaccine have been unsuccessful thus far. Giv...
متن کاملAdvancing the drug discovery and development process.
The current state of affairs in the drug discovery and development process is briefly summarized and then ways to take advantage of the ever-increasing fundamental knowledge and technical knowhow in chemistry and biology and related disciplines are discussed. The primary motivation of this Essay is to celebrate the great achievements of chemistry, biology, and medicine and to inform and inspire...
متن کاملAdvancing Clinical Trials to Streamline Drug Development.
The last decade in oncology has been marked by the identification of numerous new potential cancer targets and even more agents designed to inhibit them. The matrix of new targets, new agents, and the companion diagnostics required to identify the right patient for the right drug has created a major challenge for the clinical trial process. This has been compounded by the addition of new immuno...
متن کاملAccelerating Drug Discovery and Development Using Genomics
Despite the continuing advancements in the treatment of cancer and the introduction of new therapies, responses still vary from patient to patient. In many cases, this variation remains unexplained, making it difficult to predict who will respond. For instance, immunotherapies targeting cytotoxic T lymphocyte-associated protein 4 (CTLA-4), programmed cell death protein 1 (PD-1), and the PD-1 li...
متن کاملDrug Safety Evaluation
Despite the considerable number of newer antibacterials made available over the past decades, amoxicillin, alone or in combination with clavulanic acid, still accounts among the most widely used antibacterial agents. Although they are often considered ‘twin drugs’, they are different both in terms of antibacterial activities and of safety profile. It is well documented that the clavulanate comp...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Genomics
سال: 2018
ISSN: 2314-436X,2314-4378
DOI: 10.1155/2018/3126820